
Rhein Alleviates Cisplatin-Induced Acute Kidney Injury via Downregulation of NOX4-COX2/PGFS Signaling Pathway
Introduction Acute kidney injury (AKI), a global health problem with the increase of morbidity and mortality in each year, is characterized by a decline in renal filtration function and a rapid accumulation of metabolic waste products.1 Clinically, the …